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目的了解河南省15岁以下儿童急性弛缓性麻痹病例(Acute Flaccid Paralysis,AFP)肠道病毒感染特征,为其防控策略制定提供科学依据。方法对2009-2013年河南省AFP病例肠道病毒感染状况进行描述性分析。结果河南省AFP病例肠道病毒感染率为21.00%,其中非脊灰肠道病毒感染率为18.54%,脊灰病毒(疫苗株)感染率为2.46%。7-10月份肠道病毒感染病例占47.87%,5岁以下病例感染率为21.89%。病例疾病谱主要为吉兰巴雷综合征、短暂性肢体麻痹等,麻痹60天随访残留麻痹率为15.96%。结论河南省急性弛缓性麻痹病例肠道病毒感染以非脊灰肠道病毒为主,感染高峰为夏秋季,小年龄组儿童易感,应及时采取措施降低肠道病毒感染率。
Objective To understand the characteristics of enterovirus infection in Acute Flaccid Paralysis (AFP) in children under 15 years old in Henan Province, and to provide a scientific basis for its prevention and control strategy formulation. Methods Descriptive analysis of enterovirus infection in AFP cases from 2009 to 2013 in Henan Province. Results The infection rate of enterovirus in AFP cases in Henan province was 21.00%. The infection rate of non-polio enterovirus was 18.54%. The infection rate of poliovirus (vaccine strain) was 2.46%. In July-October, 47.87% of cases of enterovirus infection and 21.89% of cases under 5 years of age. Case disease spectrum mainly Guillain Barre syndrome, transient paralysis of limbs paralysis 60 days follow-up residual paralysis rate of 15.96%. Conclusions The majority of enterovirus infection in acute flaccid paralysis cases in Henan Province is non-polio enterovirus. The peak of infection is in summer and autumn. Children in the younger age group are susceptible. Measures should be taken to reduce the infection rate of enteroviruses in time.