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目的通过分析大连市2013年手足口病(hand-foot-mouth disease,HFMD)发病流行情况,为制定有效的预防控制策略提供依据。方法采用描述流行病学方法对2013年“中国疾病监测信息报告管理系统”报告的HFMD疫情资料和2013年大连市开展的HFMD病原学监测结果进行核实和分析。结果大连市2013年共报告HFMD 11 113例,发病率为165.33/10万,重症病例161例,死亡病例1例,发病集中在7—9月,男性多于女性,以0~6岁散居儿童为主。病原学监测结果显示,肠道病毒71型(EV71)占阳性标本的14.21%,柯萨奇病毒A组16型(Cox A16)占阳性标本的20.25%,其他肠道病毒阳性率为65.54%。抽取88份样品进行Cox A6检测,检测出39份阳性标本,阳性率44.32%。结论大连市2013年HFMD发病有明显的年龄、性别、地区和季节性差异,引起儿童HFMD的主要病原体,EV71的比例明显下降,Cox A6的比例有所上升。
Objective To analyze the incidence and prevalence of hand-foot-mouth disease (HFMD) in Dalian in 2013 and provide evidence for effective prevention and control strategies. Methods Descriptive epidemiological methods were used to verify and analyze the HFMD epidemic data reported in the 2013 China Disease Surveillance Information Reporting Management System and the etiological surveillance results of HFMD in Dalian in 2013. Results A total of 11 113 HFMD cases were reported in Dalian in 2013 with a prevalence of 165.33 / 100 000, 161 cases of severe disease and 1 case of death. The incidence of HFMD was mainly in the period of July-September. There were more males than females, and scattered children aged 0-6 Mainly. The etiological surveillance results showed that enterovirus 71 (EV71) accounted for 14.21% of positive samples, Cox A16 accounted for 20.25% of the positive samples, and the positive rate of other enterovirus was 65.54%. 88 samples were taken for Cox A6 test, 39 positive samples were detected, the positive rate was 44.32%. Conclusion In 2013, the incidence of HFMD in Dalian was significantly different according to age, sex, region and seasonality. The prevalence of HFMD in children was significantly lower than that of EV71, and the proportion of Cox A6 was increased.