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传染性单核细胞增多症(IMN)通常好发于年轻人,多数40岁以上的人被认为以前已接触过 EB 病毒而对感染具有免疫力。在以往的报道中,超过40岁的嗜异性抗体阳性的 IMN 患者仅占0.76～2.2%。由于这些病人的病情不典型,常导致延误诊断。为此作者对40岁以上病人与年轻病人的临床和实验室特征进主了回顾性对照研究。研究对象:以发热4天以上住院的17例40～78岁的 IMN 病人和17例10～17岁的IMN 病人分别作为研究组和对照组。两组均符合以下诊断标准:(1)嗜异性抗体试验阳性;(2)血淋巴细胞计数≥血白细胞
Infectious mononucleosis (IMN) usually occurs in young people, most people over the age of 40 are considered previously exposed to Epstein-Barr virus with immunity to infection. In previous reports, heterophile antibodies over 40 years old accounted for only 0.76 to 2.2% of patients with IMN. Due to the atypical illness of these patients, it often leads to delays in diagnosis. For this reason, the authors conducted a retrospective, controlled study of the clinical and laboratory characteristics of patients over 40 years of age and younger patients. Participants: 17 cases of IMN patients 40 to 78 years old and 17 cases of IMN patients aged 10 to 17 who were admitted to hospital for more than 4 days as study group and control group respectively. Both groups met the following diagnostic criteria: (1) positive for heterophile antibodies; (2) counts of lymphocytes ≥ blood leukocytes