将15只受孕大鼠分为两组,补硒组在孕期和哺乳期饮水中加有2ppm硒,对照组饮普通水,然后测定脑硒含量。补硒组母鼠为0.73±0.11μg/克湿重脑组织,对照组母鼠为0.54±0.09,两组新生鼠分别为0.32±0.02和0.25±0.03,两组生后20日龄的幼鼠分别为0.53±0.04和0.44±0.06。表明口服补充无机硒能够通过胎盘,也能通过胎鼠、幼鼠和成年鼠的血脑屏障。 Fifteen pregnant rats were divided into two groups. Selenium supplementation group added 2ppm selenium in drinking water during pregnancy and lactation. The control group received ordinary water, and then measured brain selenium content. The selenium group was 0.73 ± 0.11μg / g wet weight brain tissue, the control group was 0.54 ± 0.09, the two groups of newborn rats were 0.32 ± 0.02 and 0.25 ± 0.03, two groups of 20-day-old young rats 0.53 ± 0.04 and 0.44 ± 0.06, respectively. This suggests that oral supplementation of inorganic selenium can cross the placenta as well as the blood-brain barrier of fetal, young and adult mice.