系统性红斑狼疮(SLE)侵犯多系统多器官,临床表现复杂多样,特别在疾病早期,临床表现常缺乏特异性,而实验室各项检查亦不完全是特异性的,加之临床上不典型症状又日益增多,目前又缺乏完善的诊断标准,因之常常给诊断上带来不少困难,易于发生误诊,延误早期诊断和早期治疗时机。在我们一组病人(163例)中被确诊以前的病程不少均在一年以上,其中发病1—3年被确诊者达28%,3—6年者占17%,个别还有达10年以上者。被误诊的病种有风湿热、风湿性关节炎、肝炎、肾炎、结核、贫血、神经官能症、多发性肌炎、败血 Systemic lupus erythematosus (SLE) Invasion of multiple systems and multiple organs, the clinical manifestations of complex and diverse, especially in early stages of the disease, the clinical manifestations often lack specificity, and laboratory tests are not entirely specific, combined with clinical atypical symptoms However, there is a growing lack of sound diagnostic criteria, which often brings many difficulties in diagnosis, misdiagnosis, early diagnosis and early treatment delay. In our group of patients (163 cases) was diagnosed before the course of many of them more than one year, of which 1 to 3 years incidence of diagnosed up to 28%, 3-6 years accounted for 17%, and individually up to 10 Years or more. The disease was misdiagnosed as rheumatic fever, rheumatoid arthritis, hepatitis, nephritis, tuberculosis, anemia, neurosis, polymyositis, septicemia