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目的:分析仙方活命饮辅助治疗妇科术后感染疗效和作用机制,为临床预防和控制术后感染提供参考依据。方法:将300例妇科择期手术患者按照随机数字表法分为观察组和对照组各150例,对照组给予常规围术期用药预防术后感染,观察组在对照组治疗的基础上加用仙方活命饮。比较两组患者的术后感染发生率、血清指标和免疫功能变化情况。结果:观察组术后感染发生率为0.67%,高于对照组的4.67%,两组比较差异有统计学意义(P<0.05);观察组住院时间、开始进食时间、下床活动时间、术后用药费用均低于对照组,差异有统计学意义(P<0.05);术后两组CD+3、CD+4、CD+4/CD+8均有显著改善(P<0.05);术后3 d、术后5 d观察组CD+3、CD+4、CD+4/CD+8高于对照组,CD+8低于对照组,差异均有统计学意义(P<0.05);两组患者术后3 d、术后5 d的PCT、CRP、WBC水平均低于术前(P<0.05),观察组下降水平优于对照组,差异均有统计学意义(P<0.05)。结论:仙方活命饮应用妇科手术患者,能够有效降低术后感染发生率,改善患者的血清指标和免疫功能,缩短了患者恢复时间,值得临床推广应用。
Objective: To analyze the curative effect and mechanism of Xianfang Huozhengyin adjuvant treatment of gynecological infection and provide reference for clinical prevention and control of postoperative infection. Methods: 300 cases of gynecological elective surgery patients were divided into observation group and control group according to random number table method, 150 cases in each group. The control group was given routine perioperative medication to prevent postoperative infection. The observation group was added to the control group based on the treatment Live life drink. The incidence of postoperative infection, serum indices and immune function were compared between the two groups. Results: The incidence of postoperative infection in the observation group was 0.67%, which was higher than that of the control group (4.67%), there was significant difference between the two groups (P <0.05). The observation group’s hospitalization time, feeding time, (P <0.05). The postoperative two groups of CD + 3, CD + 4, CD + 4 / CD + 8 were significantly improved (P 0. 05); surgery The levels of CD + 3, CD + 4 and CD + 4 / CD + 8 in the observation group were significantly higher than those in the control group and CD + 8 on the 3rd and 5th postoperative day respectively. The differences were statistically significant (P <0.05). The levels of PCT, CRP and WBC in the two groups after operation were lower than those before operation (P <0.05), and the levels of PCT, CRP and WBC in the observation group were better than those in the control group on the 3rd and 5th postoperative days (P <0.05) . Conclusion: Xianfang live drink gynecological surgery patients, can effectively reduce the incidence of postoperative infection, improve patient serum indices and immune function, shorten the recovery time of patients, worthy of clinical application.