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多发性骨髓瘤的早期诊断——实验室检查的重要意义多发性骨髓瘤是一种克隆性浆细胞异常性血液系统恶性肿瘤性疾病:多发生在中老年人中.本组25例统计,其平均年龄为60.7±7.3岁,25例中最低为42岁,最高为72岁,可见老年人患病率高,随着现代人类平均寿命的延长,其患病率有增高趋势,国外流行病学统计,骨髓瘤占各种疾病的1%,占造血系统肿瘤的10%～15%.本病由于发病隐袭,又缺乏特异症状,临床表现常多种多样,极其复杂,故容易误诊和漏诊,据不同医院统计资料误诊率可达50%～60%,个别医院可达100%,主要因为骨髓瘤非典型表现所致,如以腰痛误诊为腰肌劳损,腿痛误为坐骨神经痛,女性病人全身不适,误诊为更年期综合症等等.本组一例因低热、咳嗽、血痰诊断慢支炎,一例因腰背痛,诊为风湿症,进行按摩后肋骨骨折.因而,提高对骨髓瘤的诊断水平十分必要.不仅如此,骨髓瘤的早期诊断,对其予后影响极大,本组一例多发性骨髓瘤,由于早期得到诊断治疗,中间又进行巩固化疗,至今已15年,骨髓瘤仍处于稳定阶段.骨髓瘤早期,少有骨质破坏和各系统的侵犯.而实验室检查,就是早期诊断多发性骨髓瘤的重要手段.实验室检查不仅可早期发现骨髓瘤,并对证实诊断、进行分型也有重要意义.实验室检查对早期诊断有价值的指标是:1 血沉:血沉是一种最?
Early diagnosis of multiple myeloma - the significance of laboratory tests Multiple myeloma is a clonal plasma cell abnormal blood system Malignant neoplastic disease: occurs in the middle and old people. The group of 25 cases of statistics, its The average age was 60.7±7.3 years, the lowest was 42 years in the 25 cases, and the highest was 72 years old. The prevalence rate was high in the elderly. With the increase of the average life expectancy of modern humans, the prevalence rate has an increasing trend. Foreign epidemiology Statistics, myeloma accounts for 1% of various diseases, accounting for 10% to 15% of hematopoietic system tumors. The disease due to the incidence of insidious attacks, but also the lack of specific symptoms, clinical manifestations are often varied, extremely complex, it is easy to misdiagnosis and missed diagnosis According to statistics from different hospitals, the misdiagnosis rate can reach 50% to 60%, and individual hospitals can reach 100%, mainly due to the atypical manifestations of myeloma, such as lumbar pain misdiagnosed as lumbar muscle strain, leg pain mistaken as sciatica, female Patients with general malaise, misdiagnosed as menopausal syndrome, etc. One patient in this group was diagnosed with chronic bronchitis due to low-grade fever, cough, and blood stasis. One case was diagnosed with rheumatism due to low back pain and had a rib fracture after massage. Diagnostic level is very necessary. Not only that, bone marrow The early diagnosis has a great influence on it. One case of multiple myeloma has been diagnosed and treated in the early stage. Consolidation chemotherapy has been performed in the middle. So far, myeloma has remained stable for 15 years. Early in myeloma, there are few Bone destruction and invasion of various systems. Laboratory examination is an important means for early diagnosis of multiple myeloma. Laboratory tests can not only early detection of myeloma, but also to confirm the diagnosis and classification is also important. The valuable indicators for early diagnosis are: 1 ESR: ESR is the most?