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米力农系新一代磷酸二酯酶抑制剂,它具有正性肌力和扩张血管的作用,可显著改善心力衰竭患者的血流动力学状况,但不增加心肌耗氧量。1996年9月～1997年8月我们采用国产米力农治疗急性心肌梗死并发泵衰竭14例,同时进行心功能指标和临床疗效观察。 1 对象与方法 1.1 对象:本组14例,均系急性心肌梗死,急性广泛前壁6例,前壁4例,前壁加下壁4例,其中男性10例,女性4例,年龄63～84岁,平均年龄72.9岁。根据急性心肌梗死泵衰竭按Killip分级标准,Ⅲ级8例,Ⅳ级5例,Ⅴ级1例。
Millenin, a new generation of phosphodiesterase inhibitors, has positive inotropic and dilated blood vessels and significantly improves hemodynamics in patients with heart failure without increasing myocardial oxygen consumption. From September 1996 to August 1997, we used homemade milrinone to treat 14 cases of acute myocardial infarction complicated with pump failure. At the same time, the cardiac function and clinical efficacy were observed. 1 Subjects and Methods 1.1 Subjects: The group of 14 patients, all acute myocardial infarction, acute wide anterior wall in 6 cases, anterior wall in 4 cases, plus anterior wall in 4 cases, including 10 males and 4 females, aged 63 ~ 84 years old, average age 72.9 years old. According to the Killip grading standard of acute myocardial infarction pump failure, there were 8 cases of grade Ⅲ, 5 cases of grade Ⅳ and 1 case of grade Ⅴ.