论文部分内容阅读
选取目前普遍认为有抑菌作用的4种中药(黄连、白附子、复方黄连素、双黄连粉针剂),对其浸出液常规浓缩后采用MIC法,分别测定对金黄色葡萄球菌与大肠杆菌的体外最小抑菌浓度。采用同样的检测方法,分别检测3种常用抗生素(青霉素、诺佛沙星、阿莫西林)的最小抑菌浓度。通过原子吸收光谱法检测出单位浓度下上述中药的重金属含量。结合通过对比常用抗生素MIC值,得出的单个疗程中中药所需的最小药量,计算出单个疗程内服用中药摄入的重金属总量。分析结果表明在确定疗效下,疗程内所需摄入中药的重金属总量普遍超标。
Four kinds of traditional Chinese medicines (Coptis chinensis, Baifuzi, compound berberine, and Shuanghuanglian injection), which are generally considered to have antibacterial activity, were selected. The MIC was applied to the conventional concentration of the leachate, and the concentrations of Staphylococcus aureus and Escherichia coli were determined in vitro. Minimum inhibitory concentration. Using the same test method, the minimum inhibitory concentrations of three commonly used antibiotics (penicillin, norfloxacin, amoxicillin) were determined. The content of heavy metals in the above-mentioned Chinese medicines at unit concentration was detected by atomic absorption spectrometry. By comparing the MIC values of the commonly used antibiotics, the minimum drug dose required for the traditional Chinese medicine in a single course of treatment was calculated, and the total amount of heavy metals taken by the traditional Chinese medicines during a single treatment course was calculated. The results of the analysis showed that the total amount of heavy metals required for Chinese herbal medicine intake during the course of treatment was generally excessive.