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转移是恶性肿瘤最重要的生物学特性,一般实体瘤在诊断时就有2/3左右已经存在转移,而转移也恰恰是肿瘤治疗失败的主要原因,绝大多数肿瘤患者最终死于转移瘤生长的结果或者治疗的毒副反应。因此对于肿瘤转移的早期诊断和合理治疗是延长肿瘤患者生存率的主要手段。肿瘤转移是一个多步骤的复杂过程,其机制至今尚未完全阐明,涉及到肿瘤细胞与周围微环境的相互作用,其中血管内
Metastasis is the most important biological characteristics of malignant tumors, the general solid tumor at the time of diagnosis there are about 2/3 of the transfer already exists, and metastasis is precisely the main reason for the failure of cancer treatment, the vast majority of patients eventually died of metastatic tumor growth The result of the treatment or the side effects. Therefore, the early diagnosis and reasonable treatment of tumor metastasis is the main means to extend the survival rate of cancer patients. Tumor metastasis is a complex, multi-step process whose mechanism has not yet been fully elucidated and involves the interaction of tumor cells with the surrounding microenvironment. The intravascular