本文报告用CFW小鼠吸入苯的慢性实验研究,苯浓度14.6mg/L,每天3小时,每周6天,染毒半年至一年,结果造成了比较典型的再生障碍性贫血模型。表现为全血细胞减少、骨髓有核细胞数减少、骨髓粒细胞增殖相对减少、成熟障碍。骨髓粒细胞向血液输出率相当于正常的1.4倍。骨髓组织形态检查见到明显脂肪化,未见纤维化等。作者初步提出了关于苯再障模型的基本特征。 This paper reports the chronic experimental study of benzene inhalation in CFW mice. The concentration of benzene was 14.6mg / L, 3 hours a day, 6 days a week, and the toxicity was half a year to a year. The typical model of aplastic anemia was caused. The performance of pancytopenia, decreased number of bone marrow nucleated cells, bone marrow granulocyte proliferation decreased, maturation disorder. Bone marrow granulocyte output rate to the blood equivalent to 1.4 times the normal. Metabolic bone marrow see significant fatty, no fibrosis and so on. The author initially proposed the basic characteristics of benzene aplastic anemia model.