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目的 探讨心电图在心脏再同步化治疗(CRT)应答中的预测价值.方法 选取接受CRT(D)的患者作为研究对象,术后随访至少6个月,根据临床效果分为应答组与无应答组.分析术前术后患者QRS波时限,术前ST段下移值、QTc间期、有无病理性Q波及QRS波切迹对CRT应答是否有预测价值.结果 共入选51例患者,6例失访,剩余45例纳入研究,24例CRT有应答,比例为53.3％,死亡8例.应答组术前心电图存在QRS波切迹明显低于无应答组(5/24 vs 16/21例,P=0.03);应答组术后心电图QRS波时限显著短手无应答组[(137.1±27.9)ms vs(166.3±28.5) ms,P＜0.05],且对CRT预后有预测价值(OR=0.964,95％ CI 0.942～0.998,P=0.004),分界值为125 ms.结论 心电图对CRT的应答有一定的预测作用.“,”Objective To evaluate the predictive value of electrocardiography for response to cardiac resynchronization therapy (CRT).Methods Patients with CRT were enrolled in this study.Patients were followed up for at least 6 months,according to the clinical effect for response group and nonresponse group.The value for QRS duration,QRS notch,ST-segment depression,pathological Q wave,and QTc duration to predict response to CRT was assessed.Results A total of 51 patients were enrolled in the study,and 24 patients responded to CRT (53.3％).Preoperative rate of QRS wave notch in the response group was significantly lower than that of the nonresponse group(5/24 vs 16/21,P=0.03),postoperative QRS duration of the response group was significantly lower than that of the nonresponse group [(137.1 ±27.9) ms vs (166.3 ±28.5) ms,P＜0.05],and can predict clinical prognosis of cardiac resynchronization therapy(OR =0.964,95％ CI 0.942-0.998,P =0.004).Conclusion Electrocardiography has predictive value for response to CRT.