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目的探讨无创正压通气(NPPV)治疗哮喘所致呼吸衰竭的临床疗效。方法选取2009年6月至2012年12月宜阳县人民医院收治的哮喘所致呼吸衰竭患者62例,将入选患者随机分为观察组和对照组,每组31例,对照组患者采取常规治疗,观察组在对照组的基础上加用无创正压通气治疗,治疗48 h后,观察比较两组患者的动脉氧分压(PaO2)、动脉二氧化碳分压(PaCO2)、pH值、心率(HR)及呼吸频率(RR)等指标及临床症状、并发症等情况。结果治疗48 h后观察组患者的PaO2、PaCO2、pH值及RR等几项指标和对照组相比,差异有统计学意义(P<0.05),而观察组的HR和对照组相比较,差异无统计学意义(P>0.05)。观察组患者改为有创机械通气的发生率为6.45%,和对照组(25.81%)相比,差异有统计学意义(P<0.05)。而两组患者的病死率比较差异无统计学意义(P>0.05)。结论对于哮喘导致的呼吸衰竭患者,在常规治疗的基础上,早期及时正确采取无创正压通气治疗,同时应做好相关护理工作,可以有效改善患者血气指标、减少患者并发症,降低病死率、提高患者治愈率,有一定的临床推广意义。
Objective To investigate the clinical efficacy of noninvasive positive pressure ventilation (NPPV) in treating respiratory failure caused by asthma. Methods Sixty-two patients with respiratory failure caused by asthma were selected from June 2009 to December 2012 in Yiyang People’s Hospital. The patients were randomly divided into observation group and control group, with 31 cases in each group. Patients in control group were treated routinely , The observation group was treated with non-invasive positive pressure ventilation on the basis of the control group. After 48 hours of treatment, the PaO2, PaCO2, pH, HR ) And respiratory rate (RR) and other indicators and clinical symptoms, complications and so on. Results Compared with the control group, the PaO2, PaCO2, pH and RR of the observation group after 48 hours of treatment were significantly different (P <0.05), while the HR of the observation group was significantly lower than that of the control group No statistical significance (P> 0.05). The incidence of invasive mechanical ventilation in the observation group was 6.45%, which was significantly different from that in the control group (25.81%) (P <0.05). The two groups of patients with no significant difference in mortality (P> 0.05). Conclusions For patients with respiratory failure caused by asthma, noninvasive positive pressure ventilation should be taken promptly and correctly on the basis of routine treatment. At the same time, nursing work should be done well, which can effectively improve blood gas indexes, reduce patient complications, reduce mortality, Improve the cure rate of patients, there is a certain clinical significance.