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目的探讨喜炎平注射液和利巴韦林注射液治疗普通型儿童手足口病的成本与疗效,为临床选药提供参考依据。方法将该院2014年4月—2017年2月间收治手足口病患儿130例临床资料进行回顾性分析,按照治疗方式不同分为试验组与对照组各65例,给予试验组患儿联用喜炎平注射液和利巴韦林注射液治疗,给予对照组患儿单用利巴韦林注射液治疗,比较两组患儿治疗情况。结果经治疗后观察统计,试验组患儿以治疗总有效果%明显优于对照组(P<0.05),且试验组患儿体热消退时间、临床症状与体征改善时间明显少于对照组(P<0.05),且治疗试验组患儿总成本(2.89±0.91)万元明显低于治疗对照组患儿成本(3.17±0.41)万元。结论对普通型儿童手足口病选取喜炎平注射液和利巴韦林注射液联合治疗具有较好疗效,可明显缩短患儿治疗时间,降低并发症的发生,安全性更高,同时有效减少临床治疗患儿成本,可于临床中推广及应用。
Objective To explore the cost and curative effect of Xiyanping injection and ribavirin injection in treating common hand-foot-mouth disease in children and provide a reference for clinical drug selection. Methods Clinical data of 130 children with HFMD treated in our hospital from April 2014 to February 2017 were retrospectively analyzed. According to the different treatment methods, 65 cases were divided into experimental group and control group, Treatment with Xiyanping injection and ribavirin injection, the control group of children treated with ribavirin alone, the treatment of children in two groups were compared. Results After treatment, the statistics showed that the total effective rate in treatment group was significantly higher than that in control group (P <0.05), and the time of body heat extinction, the clinical symptoms and signs of improvement in experimental group were significantly less than those in control group P <0.05), and the total cost of treatment in experimental group (2.89 ± 0.91) million yuan was significantly lower than that of the control group (3.17 ± 0.41) yuan. Conclusions The combination of Xiyanping injection and ribavirin injection in common children with HFMD is effective and can shorten the treatment time and reduce the incidence of complications in children with HFMD. Clinical treatment of children with costs, can be in clinical promotion and application.