喻某,女,49岁。1978年开始显颈粗、食欲亢进(每餐8～9两)、多汗、性情急躁,曾在我院诊断为“甲亢”,服中药及海带治疗。1982年患者饮食减退(每餐2两),腹胀、乏力、消瘦、心悸、不能胜任体力劳动。1983年11月体重显著减轻,怕冷、厌油、倦怠、少言懒语于1984年2月15日求医入院。体检:体温36.5℃,脉搏90次/分,血压正常,身高1.56米,体重29公斤。慢性重病容,极度消瘦,面容焦悴,表情淡漠。眼征(一)。双侧甲状腺 Yu Mou, female, 49 years old. Beginning in 1978 coarse neck, appetite hyperthyroidism (each meal 8 to 9 two), sweating, impatient, has been diagnosed in our hospital as “hyperthyroidism”, taking traditional Chinese medicine and kelp treatment. In 1982 the patient’s diet decreased (two meals per meal), abdominal distension, fatigue, weight loss, heart palpitations, can not do manual labor. November 1983 significantly reduced body weight, cold, tired of oil, fatigue, lazy words in February 15, 1984 for admission. Physical examination: body temperature 36.5 ℃, pulse 90 beats / min, normal blood pressure, height 1.56 meters, weight 29 kg. Chronic severe illness, extremely thin, scorching face, expression of indifference. Eye sign (a). Bilateral thyroid