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目的:观察西黄解毒胶囊对Ⅲ期大肠癌术后患者复发转移的影响。方法:将52例大肠癌术后患者为随机分为对照组与治疗组,每组26例,两组均应用规范的术后辅助放化疗,治疗组同时联合西黄解毒胶囊,观察两组中位复发转移时间、1～3年复发转移率及患者生活质量影响。结果:大肠癌患者术后1年、2年、3年复发转移率对照组分别为41.66%,79.16%和91.66%;治疗组分别为15.38%,50.00%和57.69%,治疗组与对照组比较,术后第2、3年有统计学差异(P<0.05及P<0.01),大肠癌患者术后中位复发转移时间对照组为14个月,治疗组为21个月,两组有统计学差异(P<0.05)。治疗组治疗前后KPS评分分别为73.35±6.21和81±5.47,统计学有明显差异(P<0.05)。结论:大肠癌患者应用西黄解毒胶囊可以降低术后复发转移,改善生活质量。
Objective: To observe the effect of Xihuang Jiedu capsule on the recurrence and metastasis of postoperative patients with stage Ⅲ colorectal cancer. Methods: Fifty-two patients with colorectal cancer were randomly divided into control group and treatment group, with 26 cases in each group. Both groups received standard adjuvant chemoradiotherapy and chemotherapy. The treatment group also combined with Xihuang Jiedu Capsule. Bit recurrence and metastasis, 1 to 3 years recurrence and metastasis rate and quality of life of patients. Results: The recurrence and metastasis rates of patients with colorectal cancer at 1 year, 2 years and 3 years after operation were 41.66%, 79.16% and 91.66% in the control group, 15.38%, 50.00% and 57.69% in the treatment group, respectively (P <0.05 and P <0.01). The median time of postoperative recurrence and metastasis in patients with colorectal cancer was 14 months in the control group and 21 months in the treatment group, with statistical significance Learning difference (P <0.05). The KPS scores before and after treatment in the treatment group were 73.35 ± 6.21 and 81 ± 5.47, respectively, with statistically significant differences (P <0.05). Conclusion: The application of Xihuang Jiedu capsule in patients with colorectal cancer can reduce postoperative recurrence and metastasis and improve the quality of life.