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目的探讨分析了急性脑梗死患者血清中同型半胱氨酸、C反应蛋白及D2聚体与急性脑梗死发生的关系。方法对我院2010年到2011年收治的60例急性脑梗死患者(观察组)和60例健康志愿者(对照组)的血清中同型半胱氨酸、C反应蛋白及D2聚体的含量进行分析比较,并对患者美国卫生研究院卒中量表评分进行分析。结果观察组患者血清中同型半胱氨酸、C反应蛋白及D2聚体的含量显著高于对照组,两组比较具有统计学意义(P<0.05);其中观察组患者中大面积脑梗死组(B组)患者血清中同型半胱氨酸、C反应蛋白及D2聚体的含量显著高于小面积脑梗死组(A组),两组比较具有统计学意义(P<0.05)。同型半胱氨酸、C反应蛋白及D2聚体的含量与急性脑梗死患者美国卫生研究院卒中量表评分无相关性。结论测定血清中同型半胱氨酸、C反应蛋白及D2聚体对急性脑梗死患者的临床诊断和分析有着重要意义。
Objective To investigate the relationship between serum homocysteine, C-reactive protein and D2-dimer and the occurrence of acute cerebral infarction in patients with acute cerebral infarction. Methods The levels of homocysteine, C-reactive protein and D2-dimer in serum of 60 patients with acute cerebral infarction (observation group) and 60 healthy volunteers (control group) who were admitted to our hospital from 2010 to 2011 were analyzed. Analysis and comparison, and the patient’s American Academy of Health Stroke Scale score analysis. Results The levels of serum homocysteine, C-reactive protein and D2-dimer in the observation group were significantly higher than those in the control group, with statistical significance (P <0.05). Among the observation group, the large area cerebral infarction group The serum levels of homocysteine, C-reactive protein and D2-dimer in group B were significantly higher than those in group A (P <0.05). Homocysteine, C-reactive protein and D2-dimer levels were not associated with the US National Institutes of Health Stroke Scale score in patients with acute cerebral infarction. Conclusion The determination of serum homocysteine, C-reactive protein and D2-dimer in patients with acute cerebral infarction clinical diagnosis and analysis of great significance.