黄芪建中汤联合西药治疗消化性溃疡随机平行对照研究

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[目的]观察黄芪建中汤联合西药治疗消化性溃疡疗效。[方法]使用随机平行对照方法,将200例门诊患者按随机数字表法分为两组。对照组100例雷尼替丁,150mg/次,2次/d。阿莫西林,1g/次,3次/d。吗叮啉,20mg/次,3次/d,餐前30min口服。治疗组100例黄芪建中汤(黄芪20g,炒白芍18g,桂枝、生姜各9g,炙甘草6g,大枣5枚,饴糖30g),1剂/d,水煎200mL,早晚口服。泛吐清水加干姜、吴茱萸、法半夏、茯苓;寒盛合附子理中汤;脾虚湿盛加陈皮、半夏;肾阳虚加巴戟天、仙茅;胃阴虚加石斛、沙参、玉竹;淤血合失笑散;肝气郁积合柴胡疏肝散;饮食停滞合保和丸;西药治疗同对照组。连续治疗28d为1疗程。观测临床症状、不良反应。治疗1疗程,判定疗效。[结果]治疗组痊愈60例,显效37例,有效2例,无效1例,总有效率99.00%。对照组痊愈47例,显效33例,有效11例,无效9例,总有效率89.00%。治疗组疗效优于对照组(P<0.05)。[结论]黄芪建中汤联合西药治疗消化性溃疡效果显著,值得推广。 [Objective] To observe the curative effect of Huangqi Jianzhong Decoction combined with western medicine on peptic ulcer. [Methods] Using randomized parallel control method, 200 outpatients were divided into two groups according to random number table. 100 patients in the control group ranitidine, 150mg / time, 2 times / d. Amoxicillin, 1g / time, 3 times / d. Domperidone, 20mg / time, 3 times / d, 30min oral meal. The treatment group 100 cases of Astragalus Jianzhong Decoction (Astragalus 20g, fried peony root 18g, Guizhi, ginger 9g, Zhigancao 6g, jujube 5, caramel 30g), 1 / d, decoction 200mL, sooner or later oral. Pan spit water plus ginger, Evodia, France Pinellia, Poria; Arisaemia in the soup; spleen wet sheng plus dried tangerine peel, Pinellia; plus Yangmianji, Curculigo; Stomach yin deficiency plus Dendrobium, Radix , Polygonatum; congestion blood loss laughter; liver qi stagnation combined Chaihu Shugan San; diet stagnation and Paul pill; western medicine treatment with the control group. Continuous treatment 28d for a course of treatment. Observed clinical symptoms, adverse reactions. Treatment of a course of treatment to determine the efficacy. [Results] The treatment group cured 60 cases, 37 cases markedly effective in 2 cases, 1 case of ineffective, the total effective rate was 99.00%. In the control group, 47 cases were cured, 33 cases were markedly effective, 11 cases were effective, 9 cases were ineffective, and the total effective rate was 89.00%. The treatment group was better than the control group (P <0.05). [Conclusion] Astragalus Jianzhong decoction combined with western medicine has obvious effect on treating peptic ulcer and should be popularized.
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