选择性双重滤过膜式血浆置换疗法(DFPP)是选择性除去或减少病理性血浆成分的血浆分离方法。Agishi 1979年首次用于临床,已在多学科领域发挥其独特的治疗作用,尤其对系统性红斑狼疮、类风湿性关节炎、高脂血症等疗效肯定。我院自1992年起对8例类风湿性关节炎(RA)进行了38次DFPP治疗,疗效满意。 对象与方法 一、本组8例均符合ARA的RA诊断标准。男2例、女6例,年龄26～65岁,平均40岁。其中1例合并干燥综合征。病程0.5～16年,平均8.9年。所有病例经确诊后均予以激素及非甾体抗 Selective double-filtration membrane-based plasmapheresis (DFPP) is a plasma separation method that selectively removes or reduces pathological plasma components. For the first time in clinical practice in 1979, Agishi has played a unique therapeutic role in multidisciplinary fields, especially in the areas of systemic lupus erythematosus, rheumatoid arthritis and hyperlipidemia. Our hospital since 1992, 8 cases of rheumatoid arthritis (RA) were 38 DFPP treatment, with satisfactory results. Subjects and methods First, the group of 8 patients were in line with RA diagnostic criteria ARA. 2 males and 6 females, aged 26 to 65 years, an average of 40 years old. One case combined with Sjogren’s syndrome. Course of disease 0.5 to 16 years, an average of 8.9 years. All cases were diagnosed with hormone and non-steroidal anti-body