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意大利佛罗伦萨市Careggi 医院的Dr．Martino Cellerin及其同事在Stroke杂志上报告,静脉注射血小板糖蛋白Ⅱb／Ⅲ a拮抗剂替罗非班(tirofiban,TF)和机械溶栓似乎有望用于主要脑血管闭塞引起的严重卒中患者的治疗。他们指出,糖蛋白拮抗剂一直被用于急性缺血患者的治疗,此类制剂联合溶栓药物使用可加速血块溶解。为进一步研究,他们分析了因主要脑动脉急性闭塞引起卒中
Dr. Careggi Hospital, Florence, Italy Martino Cellerin and colleagues report in Stroke that intravenous administration of the platelet glycoprotein IIb / IIIa antagonist tirofiban (TF) and mechanical thrombolysis appears promising for treatment of patients with severe stroke due to major cerebrovascular occlusion . They point out that glycoprotein antagonists have been used in the treatment of acute ischemic patients and that such agents in combination with thrombolytic drugs can accelerate clot lysis. For further study, they analyzed the stroke caused by acute occlusion of the main cerebral artery