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目的:讨论新生儿感染性疾病中血清降钙素原(PCT)的早期诊断价值。方法:选择新生儿肺炎31例、新生儿败血症54例作为研究组,选同期住院的非感染性疾病新生儿53例为观察组,对3组患儿进行血清降钙素原检测,对比3组患儿入院后第1天和1周后的降钙素原结果。结果:治疗前新生儿肺炎组和新生儿败血症组PCT较对照组明显升高,差异有统计学意义(P<0.05),而三组治疗前后PCT对比差异有统计学意义(P<0.05)。结论:血清降钙素原有助于早期诊断、鉴别、判断病情严重程度,并且为临床药物应用提供了可靠的依据。
Objective: To discuss the early diagnostic value of serum procalcitonin (PCT) in neonatal infectious diseases. Methods: Thirty-one cases of neonatal pneumonia and 54 cases of neonatal sepsis were selected as study group. Fifty-three newborns with noninfectious disease hospitalized during the same period were selected as the observation group. Serum procalcitonin Procalcitonin results on day 1 and week 1 after admission to hospital. Results: Before treatment, the PCT of neonatal pneumonia group and neonatal sepsis group was significantly higher than that of the control group (P <0.05), while the difference of PCT between the three groups before and after treatment was statistically significant (P <0.05). CONCLUSION: Serum procalcitonin is helpful for early diagnosis, identification and judgment of the severity of illness, and provides a reliable basis for clinical drug application.