患有肾脏严重损害的病人常常需要改变他们的用药方式。由于肾脏的排泄功能受到损坏,不仅有些药物的疗效受到损坏;而且更为常见的是产生毒性作用。严重的肾脏损害在临床上可出现各种不同的情况,有的患者有不可逆的肾脏疾病,他们靠人工透析器来维持生命;有的患有进行性肾脏疾病,如慢性肾小球肾炎等。严重的肾脏损害可继发于糖尿病或高血 Patients with severe kidney damage often have to change their medication. As the renal excretory function is damaged, not only is the efficacy of some drugs damaged, but it is more common to have toxic effects. Serious kidney damage in clinical conditions can occur in a variety of cases, some patients have irreversible kidney disease, they rely on artificial dialysis to maintain their lives; Some patients with progressive kidney disease, such as chronic glomerulonephritis. Serious kidney damage can be secondary to diabetes or high blood