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目的:探讨罗哌卡因复合舒芬太尼在潜伏期分娩镇痛中的应用效果。方法:择取2015年1月~2016年1月我院收治的产妇102例,随机分为A、B、C组,各组34例,A组产妇宫口开至1 cm时采取罗哌卡因复合舒芬太尼硬膜外自控分娩镇痛,B组产妇宫口开至3 cm时采取罗哌卡因复合舒芬太尼硬膜外自控分娩镇痛,C组产妇未采取分娩镇痛,比较两组第一产程潜伏期、活跃期及第二产程持续时间及宫缩时视觉模拟评分(VAS)评分,比较各组产妇出血量、新生儿体质量及胎儿娩出后1 min、5 min Apgar评分,记录各组治疗30 d后不良反应。结果:A组、B组第一产程潜伏期持续时间明显较C组延长,活跃期持续时间较C组明显缩短,差异有统计学意义(P<0.05);A组产妇宫颈口开至2 cm和cm时VAS评分低于B组和C组,差异有统计学意义(P<0.05);A组、B组产妇在活跃期、第二产程时VAS评分低于C组,差异有统计学意义(P<0.05);各组产妇出血量、新生儿体质量、Apgar评分比较均无统计学意义(P>0.05);C组抑郁症发生率均高于较A组和B组,差异有统计学意义(P<0.05)。结论:从产妇潜伏期开始应用罗哌卡因复合舒芬太尼进行分娩镇痛的效果较好,具有良好的应用价值。
Objective: To investigate the effect of ropivacaine combined with sufentanil on labor analgesia of latent period. Methods: A total of 102 maternal women admitted to our hospital from January 2015 to January 2016 were randomly divided into A, B and C groups, with 34 cases in each group. A group of maternal uterine cervix was opened to 1 cm while taking ropivacaine Due to compound sufentanil epidural self-controlled labor analgesia, B group maternal uterine opening to 3 cm when ropivacaine combined sufentanil epidural labor analgesia, C group of maternal did not take childbirth analgesia , The latency of the first stage of labor, the duration of the second stage of labor and the visual analog scale (VAS) score of contractions were compared between the two groups. The amount of maternal bleeding, the newborn’s body weight and the 1 min, 5 min after the baby was delivered were compared Score, record the adverse reactions after 30 days of treatment in each group. Results: The duration of the first stage of labor in group A and group B was longer than that of group C, and the duration of the active stage was shorter than that of group C (P <0.05). In group A, the cervix was open to 2 cm and cm, the VAS score was lower than that of the B and C groups (P <0.05). The VAS scores of the A and B groups in the active stage and the second stage of labor were lower than those in the C group (P <0.05), the difference was statistically significant P <0.05). There was no significant difference in the amount of maternal bleeding, neonatal body weight and Apgar score in each group (P> 0.05). The incidence of depression in group C was higher than that in group A and group B Significance (P <0.05). Conclusion: The effect of labor analgesia with ropivacaine and sufentanil starting from the maternal incubation period is good and has good application value.