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目的 :探索治疗浅部真菌感染的有效疗法。方法 :将 1 80例皮肤浅部粘膜真菌感染患者随机分组。A组 :单独口服伊曲康唑胶囊 ;B组 :口服伊曲康唑同时予硝酸咪康唑外用 ;C组 :单独外用硝酸咪康唑霜。结果 :伊曲康唑胶囊与硝酸咪康唑霜联用组的自觉症状明显改善时间和 60 %皮损消失时间优于伊曲康唑 7日疗法组 (P <0 0 5) ,临床治愈率优于硝酸咪康唑霜组 (P <0 0 5)、与伊曲康唑 7日疗法组无显著性差异 (P>0 0 5)。结论 :硝酸咪康唑霜与伊曲康唑胶囊联合应用 ,疗效比单一用药显著 ,治愈率达 83 3 % ,值得临床推广
Objective: To explore the effective treatment of superficial fungal infection. Methods: One hundred and eighty cases of superficial mucosal fungal infections were randomly divided into two groups. Group A: oral itraconazole capsules alone; Group B: oral itraconazole while miconazole nitrate external use; Group C: external topical miconazole nitrate cream. Results: Itraconazole and miconazole nitrate cream combination group significantly improved the time to symptoms and 60% lesions disappear time than itraconazole 7-day treatment group (P <0 05), the clinical cure rate is better than Miconazole nitrate cream group (P <0 05), and itraconazole 7-day treatment group no significant difference (P> 0 05). Conclusions: The combination of miconazole nitrate cream and itraconazole capsule has a significant curative effect compared with single administration, with a cure rate of 83.3%, which is worthy of clinical promotion