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目的分析甲型H1N1流感确诊病例的临床特征,探讨治疗方法,为防治提供依据。方法对229例甲型H1N1流感确诊病例的一般情况,临床表现,实验室检查,胸部X线,治疗方法进行统计、分析。结果甲型H1N1流感确诊病例平均年龄18.12岁,男:女为3.09:1,临床症状、体征中前三位分别是咳嗽157例、咽痛135例、咳痰50例和发热228例、咽部充血225例。白细胞总数降低40例、中性粒细胞和淋巴细胞降低占多数。血清酶升高:ALT22例、AST29例、LDH26例、CK45例、CKMB8例,血脂降低:CHO83例、TG108例。胸部X线异常6例,单侧肺炎1例,双侧肺炎5例。中药使用率100%,达菲使用率35.80%,抗生素使用率16.59%,其它抗病毒药物使用率13.10%。平均住院5.21d。结论甲型H1N1流感确诊病例以咳嗽、咽痛、咳痰、发热、咽部充血和肺部病变居多,CT检出肺部病变多,绝大部分血白细胞降低,心肌和肝脏最易受侵害,药物治疗效果好,病程较短。
Objective To analyze the clinical characteristics of confirmed cases of Influenza A (H1N1), discuss the treatment methods and provide basis for prevention and treatment. Methods The general situation, clinical manifestations, laboratory tests, chest X-ray and treatment of 229 cases of confirmed influenza A (H1N1) were statistically analyzed. Results The average age of confirmed cases of Influenza A (H1N1) was 18.12 years. The male and female were 3.09: 1. The top three clinical symptoms and signs were cough, 135 cases of sore throat, 50 cases of sputum and 228 cases of fever, 225 cases of congestion. The total number of white blood cells decreased 40 cases, the majority of neutrophils and lymphocytes decreased. Elevated serum enzymes: ALT22 cases, AST29 cases, LDH26 cases, CK45 cases, CKMB8 cases, hypolipidemia: CHO83 cases, TG108 cases. Chest X-ray abnormalities in 6 cases, 1 case of unilateral pneumonia, bilateral pneumonia in 5 cases. The usage rate of traditional Chinese medicine was 100%, Tamiflu usage rate was 35.80%, antibiotic usage rate was 16.59%, and other antiviral drug usage rate was 13.10%. Average hospitalization 5.21d. Conclusions The confirmed cases of Influenza A (H1N1) are mostly cough, sore throat, expectoration, fever, pharyngeal hyperemia and pulmonary diseases. Most of the lung lesions were detected by CT, the majority of white blood cells were decreased, the myocardium and liver were the most vulnerable, Good drug treatment, shorter duration.