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64只大鼠随机分为阻黄组及假手术组,术前及术后分期测定全血高切粘度、全血低切粘度及血浆粘度,计算红细胞刚性指数和红细胞聚集指数。结果:阻黄术后1天全血高切粘度、全血低切粘度明显上升,红细胞刚性指数、红细胞聚集指数明显增大(与假手术组比,P<0.05),并随时间推移而加重。血浆粘度变化不大。认为阻黄时血液流变学特性的改变,使红细胞不易通过毛细血管且易于聚集,引起微循环障碍,导致组织缺血、缺氧,这可能是阻黄时多器官功能不全的原因之一。
Sixty-four rats were randomly divided into sham-resistant group and sham-operated group. The whole blood high shear viscosity, whole blood low shear viscosity and plasma viscosity were measured preoperatively and postoperatively. The erythrocyte rigidity index and erythrocyte aggregation index were calculated. Results: The viscosity of whole blood and the low shear viscosity of whole blood increased obviously on the 1st day after the anti-yellowing operation. The indexes of erythrocyte rigidity and erythrocyte aggregation increased obviously (compared with the sham group, P <0.05), and with the passage of time And worse. Little change in plasma viscosity. It is considered that the changes of the rheological properties of the blood when blocking yellow make the erythrocytes not easy to pass through the capillaries and are easy to accumulate, causing microcirculation disorder, resulting in tissue ischemia and hypoxia, which may be one of the causes of multiple organ dysfunction in yellowing.