论文部分内容阅读
目的:观察逍遥散加减方联合西药治疗糖尿病合并反复泌尿系统感染的临床疗效。方法:选择86例肝郁脾虚型糖尿病合并反复泌尿系统感染患者,随机分为观察组与对照组各43例。对照组予血糖控制治疗,同时给予常规抗感染、碱化尿液治疗。观察组在对照组治疗基础上予逍遥散加减方治疗,2组均治疗14天。对2组临床疗效、尿菌转阴时间、复发情况以及治疗前后的血糖情况进行比较。结果:观察组总有效率90.70%,对照组总有效率79.07%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组空腹血糖与餐后2 h血糖均较治疗前降低(P<0.05),但2组比较,差异无统计学意义(P>0.05)。观察组0~7天和超过14天的尿菌转阴率与对照组比较,差异均有统计学意义(P<0.05)。观察组平均尿菌转阴时间短于对照组,差异均有统计学意义(P<0.05)。2组1月内复发率无统计学差异(P>0.05);观察组6月内复发率低于对照组,差异有统计学意义(P<0.05)。结论:逍遥散加减方对于糖尿病合并反复发作的泌尿系统感染具有良好的治疗作用,与常规西药联合使用,既能够提高疗效,又能够缩短尿菌转阴时间,提高转阴率,还能够有效降低感染的复发率。
Objective: To observe the clinical efficacy of Xiaoyaosan Decoction combined with Western medicine in treating diabetic patients with recurrent urinary tract infections. Methods: Eighty - six patients with diabetes mellitus and spleen deficiency syndrome complicated with recurrent urinary tract infection were randomly divided into observation group (43 cases) and control group (43 cases). Control group to give blood sugar control treatment, while giving conventional anti-infective, alkaline urine treatment. The observation group was treated with Xiaoyao San plus or minus treatment on the basis of the control group, and both groups were treated for 14 days. The clinical efficacy of 2 groups, urine negative time, recurrence and blood glucose before and after treatment were compared. Results: The total effective rate was 90.70% in the observation group and 79.07% in the control group. There was significant difference between the two groups (P <0.05). After treatment, the fasting blood glucose and 2-hour postprandial blood glucose in both groups were significantly lower than those before treatment (P <0.05). However, there was no significant difference between the two groups (P> 0.05). The negative rates of urinary bacteria in observation group from 0 days to 7 days and more than 14 days were significantly different from those in control group (P <0.05). The average urinary transit time in the observation group was shorter than that in the control group, with statistical significance (P <0.05). There was no significant difference in the recurrence rate between the two groups in one month (P> 0.05). The recurrence rate in the observation group within 6 months was lower than that in the control group (P <0.05). Conclusion: Xiaoyaosan Decoction has a good therapeutic effect on urinary tract infections with recurrent diabetes mellitus. Combined with conventional western medicine, Xiaoyaosan Decoction can not only improve curative effect, but also shorten the time of urine negative conversion, increase the rate of negative conversion, and also be effective Reduce the recurrence rate of infection.