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梭曼以毒性大、作用快、中毒难防难治而著称,是外军重点装备的化学战剂之一。脑是对梭曼极为敏感的重要靶器官。梭曼进入脑内迅速与胆碱酯酶(ChE)结合并抑制其活性,使乙酰胆碱(ACh)在突触间隙大量蓄积,从而破坏神经中枢正常功能,导致一系列生理功能的改变[1,?
Soman is known for its toxicity, quick action and prevention of poisoning. It is one of the chemical warfare agents for the key equipment of the foreign army. The brain is an important target organ that is highly sensitive to soman. Soman into the brain rapidly with cholinesterase (ChE) and inhibit its activity, so that a large number of acetylcholine (ACh) accumulation in the synaptic cleft, thereby undermining the normal function of the central nervous system, resulting in a series of physiological changes [1 ,?