论文部分内容阅读
在我们哮喘专科门诊中,选择频发性混合型成人支气管哮喘16例,用四种药物名分1、2种剂置于哮喘好发季节作综合治疗。探索应用高效和最省料的正交设计分析法作药物疗效的定量比较研究,获得满意结果。将七个因素(连同三个重要协同作用)作表头设计,随机分配得L_8(2~7)重复观察正交表。结果表明:药物及其剂量最佳选择为A_2×B_2×C_1,经正交设计方差分析P<0.01。三个月哮喘停发平均日数为42.5±15(SD),较观察前每日发作明显好转,发作程度亦减轻。文末对哮喘的防治用流程图作了概括。对正交表的设计与计算作了介绍。
In our specialist asthma clinic, we selected 16 patients with fulminant adult bronchial asthma who were divided into 1 or 2 doses with four drugs for the comprehensive treatment of asthma. Explore the application of efficient and the most material-free orthogonal design analysis for the quantitative comparative study of drug efficacy and obtain satisfactory results. Seven factors (along with three important synergies) were tabulated and randomized to give L_8 (2 to 7) repeated observations of the orthogonal table. The results showed that the best choice of drug and its dosage was A_2 × B_2 × C_1, and the variance of orthogonal design was P <0.01. The average number of days of asthma stopping at three months was 42.5 ± 15 (SD), which was significantly improved compared with that before the observation and the severity of the attack was also reduced. At the end of the prevention and treatment of asthma with a summary of the flow chart. The design and calculation of orthogonal table are introduced.