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目的观察康泉片剂在预防化疗引致恶心呕吐的疗效。方法从1996年11月至1997年7月对45例接受以顺铂或阿霉素为主联合化疗的肿瘤患者应用康泉片剂进行预防消化道反应。康泉片剂2mg均在第1天化疗前3小时口服，连续观察5天的消化道反应情况。结果控制呕吐有效率从化疗后第1天至第5天分别为：86．7％，88．9％，88．9％，91．1％和93．3％.主要不良反应为便秘（55.6％）。结论化疗前3小时口服康泉片剂2mg，可有效地预防化疗引致的消化道反应。
Objective To observe the efficacy of Kangquan tablets in preventing chemotherapy-induced nausea and vomiting. Methods From January 1996 to July 1997, Kangquan tablets were used to prevent digestive tract reaction in 45 cancer patients receiving cisplatin or doxorubicin combined chemotherapy. Kang Quan tablets 2mg were taken orally 3 hours before the first day of chemotherapy, and the digestive tract reaction was observed continuously for 5 days. Results The effective rate of controlling vomiting was from 86.7%, 88.9%, 88.9%, 91.1% and 93.3% from the 1st day to the 5th day after chemotherapy. The major adverse reaction was constipation (55.6). %). Conclusions Kangquan Tablets 2 mg orally 3 hours before chemotherapy can effectively prevent chemotherapy-induced gastrointestinal reactions.