论文部分内容阅读
观察雌二醇(Est)和孕酮(Pro)对大鼠离体血张力的影响。采用离体血管灌流方法以去甲肾上腺素(NE)0.1umol/L使血管环收缩的效应为基础:测定Est和Pro对血管张力的影响,求出最大舒张反应值(Emax)。结果:Est、Pro对离体血管有浓度和时间依赖性的舒张作用,Est的Emax为(34±5)％Pro Emax为(18±5)％。结论:Est和Pro均有一定程度的阻滞ROC作用。
The effects of estradiol (Est) and progesterone (Pro) on blood tension in vitro were observed. The effects of Est and Pro on vascular tone were determined based on the effect of norepinephrine (NE) 0.1umol / L on contracting the blood vessel rings. The maximal relaxation response (Emax) was calculated. RESULTS: Est, Pro had a concentration-dependent and time-dependent relaxing effect on isolated blood vessels. Est Emax was (34 ± 5)% and Pro Emax was (18 ± 5)%. Conclusion: Both Est and Pro block ROC to a certain extent.