Effects of rhamnolipid biosurfactant JBR425 and synthetic surfactant Surfynol465 on the peroxidase-c

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The kinetics of the recombinant Coprinus cinereus peroxidase-catalyzed2-naphthol oxidationwas investigated in the presence of rhamnolipid biosurfactant JBR425 and synthetic surfactant Surfynol465 at pH 5.5 and25°C,with concentrations of (bio)surfactants both less than critical micelle concentrations (CMC) and larger than CMC. Itwas shown that monomers of JBR425 aswell as monomers of Surfynol465 had an enhancing effect on the conversion of2-naphthol indose response manner anddid not influence the initial rate of 2-naphthol oxidation. The resultswere accounted by a scheme,which contains a stadium of enzyme inhibition by oligomeric2- naphthol oxidation products. The action of the biosurfactant’s (or synthetic surfactant’s) monomerswas explained by avoidance of the enzyme active center clothingwith oligomers. Similar results havedemonstrated the potential of rhamnolipid biosurfactant JBR425due to its biodegradability. When biosurfactants’ concentrations are larger than CMC, (bio)surfactants have an opposite effect on the oxidation of2-naphthol by peroxidase. The kinetics of the recombinant Coprinus cinereus peroxidase-catalyzed 2-naphthol oxidation was investigated in the presence of rhamnolipid biosurfactant JBR 425 and synthetic surfactant Surfynol 465 at pH 5.5 and 25 ° C with concentrations of (bio) surfactants both less than critical micelle concentrations (CMC) and larger than CMC. Itwas shown that the monomers of JBR425 aswell as monomers of Surfynol 465 had an enhancing effect on the conversion of 2-naphthol indose response manner and did not affect the initial rate of 2-naphthol oxidation. The resultswere accounted by a scheme, which contains a stadium of enzyme inhibition by oligomeric 2-naphthol oxidation products. The action of the biosurfactant’s (or synthetic surfactant’s) monomers was explained by avoidance of the enzyme active center clothingwith oligomers. Similar results have the demonstrated potential of rhamnolipid biosurfactant JBR425due to its biodegradability. When biosurfactants’ concentrations are larger than CMC, (bio) surfactan ts have an opposite effect on the oxidation of 2-naphthol by peroxidase.
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