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本文对19例12～20岁的青少年型血吸虫病性侏儒症患者的LRH和TRH下丘脑-垂体-靶腺轴兴奋试验的检测结果进行了观察。初步表明:该类患者的下丘脑-垂体-靶腺轴反馈机制大致正常。垂体GH、LH、TSH、PRL等激素并不缺乏,其储备功能亦大致正常。但周围靶腺激素不正常,这与垂体性侏儒症等明显不同,亦与中老年晚血患者的情况不同。因此,我们认为使用LRH和TRH作垂体兴奋试验将有利于本病的诊断和鉴别诊断,并有可能把该症从继发性垂体性侏儒症和晚血的分类中区分出来,这对改善其预后也不无裨益。
In this paper, we examined the results of the LRH and TRH hypothalamic-pituitary-target gland axis excitatory tests in 19 juvenile schistosomiasis dwarfism patients aged 12 to 20 years. Preliminary showed that: this type of patients hypothalamus - pituitary - gland axis feedback mechanism is generally normal. Pituitary GH, LH, TSH, PRL and other hormones are not lacking, its reserve function is also generally normal. But the surrounding target gland hormone is not normal, which is significantly different from pituitary dwarfism, but also with the late-night blood of patients with different conditions. Therefore, we believe that the use of LRH and TRH for pituitary excitation test will be beneficial in the diagnosis and differential diagnosis of the disease, and may distinguish the disease from secondary pituitary dwarfism and the classification of late blood, which is to improve its Prognosis is not without benefit.