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目的探索女性原发性骨质疏松症(Primary Osteoporosis,POP)的危险因素,为制定群体综合防治POP对策提供依据。方法共纳入研究对象413例;采用问卷调查收集研究对象人口学特征及POP危险因素的信息;运用双能X骨密度测量仪(DEXA)测定骨密度值,并进行POP诊断;使用χ2检验、Logistic回归分析POP的危险因素。结果随绝经年限增加,POP发生率增加,χ2检验差异具有统计学意义。单因素分析结果显示年龄、初潮年龄、月经状态、BMI、补钙情况、吸烟情况与POP患病的关系有统计学意义;多因素分析结果表明,在控制了其他因素后,年龄和吸烟情况与POP患病的关系有统计学意义。结论年龄增加、绝经年限增加、吸烟是患POP的危险因素。
Objective To explore the risk factors of Primary Osteoporosis (POP) in female and to provide basis for formulating population comprehensive prevention and control measures of POP. METHODS: A total of 413 subjects were enrolled in the study. Demographic characteristics and POP risk factors were collected by questionnaire survey. BMD was measured by dual energy X-ray absorptiometry (DEXA) and POP was performed. Chi-square test, Logistic Regression analysis of risk factors for POP. Results With the increase of menopause, the incidence of POP increased, the difference of χ2 test was statistically significant. Univariate analysis showed that age, menarche age, menstrual status, BMI, calcium status, smoking status and POP prevalence were statistically significant; multivariate analysis showed that after controlling for other factors, age and smoking status The prevalence of POP was statistically significant. Conclusion Age increases, menopause increases, smoking is a risk factor for POP.