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例1 陈××,女,26岁。因左上腹肿块日渐增大半年,1960年9月第一次入院。体检有胸骨压痛、巨脾,经血液及骨髓检查确诊为慢性粒细胞型白血病。用深部X线照射脾脏缓解出院;门诊以马利兰间歇治疗。在1965年9月因左上腹肿块再次肿大,左上臂肿痛4个月第二次入院。门诊拟诊恶性骨肿瘤,先入骨外科住院。检查:消瘦,左上臂皮肤紧张发亮,触及肿物周径28cm,中等硬,无明显压痛,左上肢活动障碍,其余皮肤无紫癜,浅层淋巴结不大,胸骨无压痛,肝6cm,脾13cm。血象:Hb10g,WBC15,400。骨髓象:增生极度活跃,原粒+早幼粒8.6%,中幼+晚幼粒53.4%。X线照片:左肱骨中远1/3段骨质破坏并病理性骨折。后作左肱骨病灶活检,病理报告:
Example 1 Chen × ×, female, 26 years old. As the left upper abdomen mass gradually increased six months, in September 1960 the first admission. Physical examination with sternal tenderness, splenomegaly, blood and bone marrow examination confirmed the diagnosis of chronic myelogenous leukemia. Deep X-ray irradiation spleen ease discharge; outpatient treatment with Maryland intermittent. In 1965 September due to enlargement of the left upper abdominal mass again, left upper arm swelling pain for the second time in 4 months admission. Outpatient diagnosis of malignant bone tumors, first into the surgical hospital. Check: weight loss, the left upper arm skin tension, touching the tumor circumference 28cm, moderately hard, no tenderness, left upper limb movement disorders, the rest of the skin without purpura, superficial lymph nodes, sternal no tenderness, liver 6cm, spleen 13cm . Blood: Hb10g, WBC15,400. Bone marrow: Hyperplasia extremely active, progenitor + early promyelocytic 8.6%, young + late promyelotic 53.4%. X-ray: the middle of the left humerus 1/3 bone destruction and pathological fracture. After the left humerus lesions biopsy, pathology report: