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目的：提高甲真菌病的诊断率，弥补真菌学检查的不足。方法：采用30％硝酸水溶液浸泡病甲标本3～7d的改良组织病理学方法。结果：组织病理切片的甲真菌病诊断率为86％，真菌培养为58％，直接镜检为68％。结论：此方法简便易行，患者易接受，组织清理切片的甲真菌病诊断率明显高于真菌学的方法，值得推广使用。
Objective: To improve the diagnosis rate of onychomycosis and make up for the deficiency of mycological examination. Methods: Modified histopathological method was adopted to soak the Sickle A specimen for 3 ~ 7 days with 30% nitric acid solution. Results: The diagnosis rate of onychomycosis was 86% in histopathological examination, 58% in fungal culture and 68% in direct microscopy. Conclusion: This method is simple and easy to be performed. The diagnosis rate of onychomycosis is obviously higher than that of mycosis, which is worth popularizing.