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目的探讨盐酸氨溴索在治疗慢性阻塞性肺疾病(COPD)急性发作的临床疗效。方法将112例COPD急性发作期患者随机分为两组,对照组采用抗感染、平喘等对症支持治疗,治疗组在对照组的基础上加用盐酸氨溴索60 mg静脉滴注。结果治疗组的总有效率(96.43%)明显优于对照组(82.14%),差异有统计学意义(P<0.05)。结论盐酸氨溴索能改善COPD急性发作期的肺功能,提高治疗效果。
Objective To investigate the clinical efficacy of ambroxol hydrochloride in the treatment of acute exacerbation of chronic obstructive pulmonary disease (COPD). Methods One hundred and twelve patients with acute exacerbation of COPD were randomly divided into two groups. The patients in the control group were treated with anti-infection, anti-asthma and other symptomatic supportive therapy. The treatment group was given intravenous infusion of ambroxol 60 mg on the basis of the control group. Results The total effective rate (96.43%) in the treatment group was significantly better than that in the control group (82.14%), the difference was statistically significant (P <0.05). Conclusions Ambroxol hydrochloride can improve lung function and improve the therapeutic effect in acute exacerbation of COPD.