讨论骨纤维结构不良的病因及治疗方法。本文报道16例8岁以下幼儿期骨纤维结构不良,大部分为单灶性,发生于长骨骨干,研究其临床、X 线、组织学表现和组织培养及各种治疗方法。经6个月～12年(6.2年)随访,治愈13例,复发率70%。骨纤维结构不良病变组织增生活跃、复发率高,浸润性生长,具有真性肿瘤特征。同时还根据病变纤维组织增生和化生骨化等病理过程的差别,将该病分为静止型和进展型。幼儿期骨纤维结构不良更具增生活性,多为进展型,应积极处理。 Discuss the etiology and treatment of poor bone structure. This paper reports 16 cases of young children under 8 years of age fibrous dysplasia, mostly single-focal, occurs in the long bone backbone, to study its clinical, X-ray, histological and tissue culture and various treatment methods. After 6 months to 12 years (6.2 years) follow-up, 13 cases were cured, the recurrence rate was 70%. Bony fibrous dysplasia tissue hyperplasia active, high recurrence rate, invasive growth, with true tumor characteristics. At the same time, according to the pathological changes of fibrosis and metaplasia pathological changes, the disease is divided into stationary and progressive. Toddler fibrous dysplasia more proliferative activity, mostly progressive, should be actively addressed.