By analyzing GPS, leveling and gravity observation data from the Minle, Huazangsi and Shagouhe profiles across the Qilian Mountain-Haiyuan fault during 2005～2009, the changes of these data and activity characteristics of the main faults in different time are obtained. The results show that the Changma-Erbo, Maomaoshan, Zhunglanghe and Haiyuan faults have been active in recent years. The relationship between the vertical displacement and mobile gravity data is analyzed, and the results reveal the gravity changes are mainly due to mass transfer. The results of GPS observation show that the direction of the horizontal movement velocity was almost along the fault strike in 2006～2007, while the horizontal velocity deviated from the fault direction in 2007～2008, characterized by increased eastward displacement. Further analysis upon removal of the linear trend on the time series of the N and E coordinate values of the continuous observation stations of the Crustal Movement Observation Network of China near the three profiles reveals that the Wenchuan earthquake had an effect on the observations in 2007～2008. Comparing the gravitational changes in 2008~2009 with the Bouguer gravity anomaly background, we find that the area near Minle profile is in the stage of adjustment and recovery, while the anomaly is not completely recovered around Huazangsi and Shagouhe profiles. By analyzing GPS, leveling and gravity observation data from the Minle, Huazangsi and Shagouhe profiles across the Qilian Mountain-Haiyuan fault during 2005 ~ 2009, the changes of these data and activity characteristics of the main faults in different time are obtained. The results show that the Changma-Erbo, Maomaoshan, Zhunglanghe and Haiyuan faults have been active in recent years. The relationship between the vertical displacement and mobile gravity data is analyzed, and the results reveal the gravity changes are due due to mass transfer. The results of GPS observation show that the direction of the horizontal movement velocity was almost along the fault strike in 2006 ~ 2007, while the horizontal velocity deviated from the fault direction in 2007 ~ 2008, characterized by increased eastward displacement. Further analysis upon removal of the linear trend on the time series of the N and E coordinate values ​​of the continuous observation stations of the Crustal Movement Observation Network of China near the three profiles reveals that the Wenchuan earthquake had an effect on the observations in 2007 ~ 2008. Comparing the gravitational changes in 2008 ~ 2009 with the Bouguer gravity anomaly background, we find that the area near Minle profile is in the stage of adjustment and recovery, while the anomaly is not completely recovered around huazangsi and shagouhe profiles.