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虽然已知砷中毒引起人类和动物尿中卟啉排泄型的变化 ,但是砷的特性尚不清楚。近藤雅雄等采用在卟啉代谢上对砷敏感性高的 ICR小白鼠 ,通过检测尿和粪中卟啉排泄 ,对连续经口给予的影响和BAL的恢复效果进行追踪研究。选择 4周龄 ICR小白鼠 ,按体重平均给予砷酸钠 (As5+ ) 2 0 m
Although arsenicosis is known to cause changes in porphyrin excretion in human and animal urine, the arsenic properties are not known. Kondo Masayuki et al. Used ICR mice that are highly sensitive to arsenic in the metabolism of porphyrin to investigate the effects of continuous oral administration and recovery of BAL by detecting excretion of porphyrin in urine and faeces. Four weeks old ICR mice were selected and averaged with 20 mg sodium arsenate (As5 +)