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The effect of sublingual administration and intravenous drip of nitroglycerin (SLNTG and IVNTG) on left ventricular volumes (LVVs) were studied and systolic function was quantitatively assessed with two-dimensional echocardiography (2DE) in 28 patients with myocardial infarction (MI), including 13 cases without heart failure (MI-NHF) in one group and 15 with heart failure (MI-HF) in another. The results showed that after SLNTG and IVNTG in both groups the heart rate (HR) increased significantly (P< 0.05-0.001); the systolic blood pressure (SBP) decreased significantly (P< 0.05-0.001); the diastolic blood pressure (DBP) was not significantly changed (all P>0.05); the left ventricular end-diastolic and end-systolic volumes (EDV and ESV) both significantly reduced [EDV: decreased by 5.8-11.6% (-13.2-19.0 ml), P< 0.05-0.001; ESV: decreased by 9.6-16.6% (-8.6-17.3 ml), P< 0.05-0.001)1; the left ventricular ejection fraction (LVEF) all significantly elevated (increased by 6.6%-9.4% (3.2%-3.4%), P < 0.05-0.001
The effect of sublingual administration and intravenous drip of nitroglycerin (SLNTG and IVNTG) on left ventricular volumes (LVVs) were studied and systolic function was quantitatively assessed with two-dimensional echocardiography (2DE) in 28 patients with myocardial infarction (MI), including 13 cases without heart failure (MI-NHF) in one group and 15 with heart failure (MI-HF) in another. The results showed that after SLNTG and IV NTG in both groups the heart rate (HR) increased significantly (P <0.05-0.001 ; the systolic blood pressure (SBP) decreased significantly (P <0.05-0.001); the diastolic blood pressure (DBP) was not significantly changed (all P> 0.05); the left ventricular end- diastolic and end- systolic volumes ESV: decreased by 9.6-16.6% (-8.6-17.3 ml), P <0.05-0.001 (ESV) decreased by 5.8-11.6% (-13.2-19.0 ml), respectively ) 1; the left ventricular ejection fraction (LVEF) all significantly elevated (increased by 6.6% -9.4% (3.2% -3.4 %), P <0.05-0.001