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急性上消化道出血是临床常见的急症,迅速有效的止血对预后极为重要。目前,对药物止血方法看法不一。我科于1985年4月至1988年12月采用口服去甲肾上腺素控制急性上消化道出血400例,取得满意疗效,现报道如下。一、病例选择:本文患者共633例,均为呕血与/或黑便而住急诊科观察室的病例,其中男性477例,女性156例,年龄15～76岁,平均42.6岁。患者随机分为两组,应用去甲肾上腺素为治疗组,共400例,用一般止血药(包括甲氰咪胍、止血定等)治疗为对照组,共233例。两组出血严重程度大致相似(见表1)。出血程度分级采用李氏等报道划分。
Acute upper gastrointestinal bleeding is a common clinical emergency, rapid and effective hemostasis is extremely important prognosis. At present, the methods of stopping bleeding are different. My department in April 1985 to December 1988 oral norepinephrine control of acute upper gastrointestinal bleeding in 400 cases, and achieved satisfactory results, are reported below. First, the case selection: a total of 633 patients in this paper, are vomiting and / or black and live in emergency department observation room cases, including 477 males and 156 females, aged 15 to 76 years, mean 42.6 years. Patients were randomly divided into two groups, the application of norepinephrine for the treatment group, a total of 400 cases, with the general hemostatic drugs (including cimetidine, hemostatic, etc.) treatment as the control group, a total of 233 cases. The severity of bleeding in both groups was similar (Table 1). The grade of bleeding was reported by Lee et al.