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目的:探讨妊娠期高血压疾病持续肾损害的成因及治疗。方法:追踪132例妊娠期高血压疾病患者终止妊娠或产后3个月,其中24例患者仍有肾损害,将其分为治疗组13例,对照组11例。治疗组予阿斯匹林肠溶片100mg、氨氯地平片5 mg、福辛普利纳片100 mg,均每天1次,VitE胶囊100 mg,每天三次,服用6月;对照组未作治疗。结果:经干预治疗的A组患者肾损害治愈率为76.9%,而未经干预治疗的B组患者肾损害自愈率为18.2%,有显著差异。结论:妊娠期高血压疾病肾损害持续存在时,采取干预治疗是有必要也是有效的。
Objective: To investigate the causes and treatment of persistent renal damage in hypertensive disorder complicating pregnancy. Methods: 132 patients with gestational hypertension were followed up for termination of pregnancy or 3 months postpartum. Twenty-four of the patients still had renal damage. They were divided into treatment group (n = 13) and control group (n = 11). The treatment group was treated with aspirin enteric-coated tablets 100mg, amlodipine tablets 5mg, fosinopril tablets 100mg once daily, VitE capsule 100mg three times a day for 6 months; the control group was not treated . Results: The cure rate of renal damage in group A was 76.9%, while that in group B was 18.2%. There was a significant difference. Conclusion: When renal damage of hypertensive disorder complicating pregnancy persists, it is necessary and effective to take intervention therapy.