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HCV是输血后肝炎的主要病原,但输血传播途径只能解释部分急性丙型肝炎。仍有相当一部分丙型肝炎传播途径不明,性暴露可能是其中之一。HCV序列的多样性和变异性主要反映在包膜区E_1和E_2,这种异质性常被用来调查感染源与被感染者之间病毒的相关性。 作者报告了一例35岁女性患者表现为急性丙型肝炎症状,其性伙伴为慢性丙型肝炎患者。这例女病人感染HCV8周后HCVRNA全部清除,并且随访90周HCVILNA持续阴性。对
HCV is the major cause of post-transfusion hepatitis, but the transfusion route can only explain some acute hepatitis C. There is still a significant part of the unknown route of hepatitis C transmission, and sexual exposure may be one of them. The diversity and variability of HCV sequences are mainly reflected in the envelope regions E_1 and E_2. This heterogeneity is often used to investigate the correlation between the virus source and the infected person. The authors report a 35-year-old woman presenting with symptoms of acute hepatitis C who have sex partners with chronic hepatitis C patients. HCVRNA was completely cleared in this female patient infected with HCV for 8 weeks and continued to be negative for HCVIL for 90 weeks. Correct