冠状动脉内支架植入术是治疗冠心病的重要手段之一 ,亚急性血栓形成是支架术后早期冠状动脉闭塞的主要原因 ,术后抗血小板药物的应用尤为重要。临床常用的抗血小板药物有三种 :噻氯吡啶 ,氯吡格雷及西洛他唑。多项临床试验对以上三种药物进行了研究 ,比较了它们的优缺点。目前以氯吡格雷加阿司匹林联合使用最为广泛 ,对预防冠状动脉内亚急性血栓形成的效果满意 ,消化道及血液系统副作用较少 Coronary artery stent implantation is an important means of treatment of coronary heart disease, subacute thrombosis is the main cause of coronary artery occlusion early postoperative antiplatelet drugs is particularly important. There are three commonly used clinical antiplatelet drugs: ticlopidine, clopidogrel and cilostazol. A number of clinical trials of the above three drugs were studied, compared their advantages and disadvantages. Clopidogrel plus aspirin is currently the most widely used combination to prevent subacute coronary thrombosis satisfactory results, fewer side effects of the digestive tract and the blood system