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目的：对胆石合剂治疗胆石症的疗效和安全性进行临床试验。方法：采用随便机对照方法，将病人分为治疗组１００例，对照组６０例。前者用胆石合剂（由大柴胡汤和茵陈蒿汤加减化裁制成，主要由金钱草、柴胡、川楝子、牡蛎、大黄、郁金、牛膝、香附等药组成），后者用市售胆石通。结果：在临床疗效中治疗组显效率为４３％，总有效率为８０％；对照组显效率为１８３３％，总有效率为５５％；在Ｂ超检查中治疗组显效率为４５％，总有效率为７８％；对照组显效率为１８３３％，总有效率为６０％。两组临床、Ｂ超检查显效率、总有效率比较均有统计学意义（Ｐ＜００１），结论：胆石合剂的疗效优于胆石通。提示胆石合剂对胆石症中中医辨证属气滞、湿热证者，确有疗效，并且安全无毒副作用。
Objective: To study the clinical efficacy and safety of gallstone in the treatment of cholelithiasis. Methods: Using random control method, the patients were divided into treatment group 100 cases and control group 60 cases. The former is made of gallstone mixture (composed of Dachaihu Decoction and Yinchenhao Decoction, mainly composed of Medicinal Herbs, Bupleurum, Toosendan, Oyster, Rhubarb, Turmeric, Achyranthes, With the commercial gallstone pass. Results: The effective rate of the treatment group was 43%, the total effective rate was 80%; the effective rate of the control group was 1833%, the total effective rate was 55%; in the B-ultrasound group, the effective rate was 45% , The total effective rate was 78%; the control group markedly effective rate was 1833%, the total effective rate was 60%. Two clinical, B ultrasound examination markedly effective, the total effective rate was statistically significant (P <0 01), Conclusion: gallstone mixture is superior to gallstone. Tip gallstone mixture of cholelithiasis syndrome is Qi stagnation, damp-heat syndrome, indeed effective, and safe non-toxic side effects.