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目的:观察大株红景天注射液治疗急性部分前循环脑梗死(PACI)的疗效。方法:选取南方医科大学第五附属医院2010年6月至2015年7月收治的PACI患者85例,分为治疗组45例,对照组40例。两组患者均给予扩管、溶栓、抗凝、控压、降血脂等常规治疗,治疗组在常规基础上加用大株红景天治疗,对照组在常规治疗基础上加丹参注射液治疗。在治疗前以及治疗3个月后对患者实施神经功能缺损评分(NIHSS),比较两组患者的治疗方法对同一脑梗死亚型的预后是否存在差异。结果:两组患者在入院时NIHSS比较,差异无统计学意义(P>0.05),但第90天NIHSS评分比较,差异具有统计学意义(P<0.01)。结论:大株红景天能减少PACI致残率,减轻其临床症状,改善预后,并且安全性高。
Objective: To observe the curative effect of Rhodiola rosea injection on acute partial anterior circulation cerebral infarction (PACI). Methods: 85 patients with PACI admitted to the Fifth Affiliated Hospital of Southern Medical University from June 2010 to July 2015 were divided into treatment group (45 cases) and control group (40 cases). Patients in both groups were given routine treatment such as expansion, thrombolysis, anticoagulation, pressure-control and hypolipidemic treatment. The treatment group was treated with Rhodiola rosea on a routine basis. The control group was treated with Salviae Miltiorrhizae injection on the basis of routine treatment . Neurological deficit scores (NIHSS) were administered to patients before treatment and after 3 months of treatment, and whether there was any difference in the prognosis of the same cerebral infarction subtype between the two groups. Results: There was no significant difference in NIHSS between the two groups (P> 0.05). However, the NIHSS score at the 90th day was significantly different (P <0.01). Conclusion: Rhodiola rosea can reduce PACI disability rate, reduce its clinical symptoms, improve prognosis, and high safety.