论文部分内容阅读
为了解山东地区姜虫病流行情况，对费县部分重疫区姜虫病患者进行了个案调查及病原学分离。结果表明，费县姜虫病具有典型的四大特征，即溃疡或焦痂９１．０１％（１７２／１８９）、皮疹９５．７７％（１８１／１８９）、发烧９８．９４％（１８７／１８９）、淋巴结肿大８４．６６％（１６０／１８９）；以农民为主，流行高峰在１０月中下旬。对恙虫病人分布的概率模式分析，表明当地恙虫病分布在时间、空间上均有聚集性。患者早期血清抗体阳性率７５．４２％。床边接种小鼠３２组，其中１２组分离到恙虫病立克次体（Ｒｔ）。小白鼠一般接种后５～１０天发病，解剖可见肝脾明显肿大。血清学鉴定，除部分毒株未定型外，其余均与Ｒｔ标准株Ｇｉｌｉａｍ型呈阳性反应，这与当地恙虫病人血清抗体型别一致。
In order to understand the epidemic situation of ginger and worm disease in Shandong Province, case-control and etiological separation were carried out on some patients in the endemic area of Fei County. The results showed that there were four typical characteristics in Fei County: 91.01% (172/189) of ulcer or eschar, 95.77% (181/189) of rash, 98.94% of fever (187/189) ), Enlarged lymph nodes 84.66% (160/189); mainly peasants, epidemic peak in late October. The probability model analysis of the distribution of scrub typhus showed that the distribution of scrub typhus in local time and space are aggregated. The positive rate of early serum antibody in patients was 75.42%. 32 mice were inoculated to the bedside, of which 12 were isolated from Rickettsia tsutsugamushi (Rt). Mouse inoculation 5 to 10 days after the onset of the general appearance of liver and spleen can be significantly enlarged anatomy. Serological identification, in addition to some strains are not set, the rest are positive with Rt standard strain Giliam type, which is consistent with the type of local scrub typhus patients serum antibody.