从九华香茶菜的干叶中得到6种成分。除β-谷甾醇和齐墩果酸外,四种为二萜类化合物,其中三种为已知二萜成分excisanin A、excisanin B和macrocalyxin A;另一种为新的二萜化合物,命名为九华香茶菜甲素。体外抗癌实验证明,九华香茶菜甲素对Hela细胞和肺癌细胞(A_(549))均有抑制作用。通过理化常数的测定、光谱分析和衍生物的制备,测定了其结构为(1)式。 Six ingredients were obtained from the dry leaves of Jiuhua Xiangcai. In addition to β-sitosterol and oleanolic acid, four are diterpenoids, of which three are known diterpene compounds excisanin A, excisanin B, and macrocalyxin A; the other is a new diterpene compound, named Jiuhua Xiangcaijiasu. In vitro anti-cancer experiments demonstrated that Jiuhuaxin A inhibited both Hela cells and lung cancer cells (A_(549)). Through the determination of physicochemical constants, spectral analysis and the preparation of derivatives, the structure was determined as (1).