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患者,女,67岁.因“膀胱癌”在当地医院行膀胱部分切除术,术后1周按常规采用塞(口替)哌膀胱内灌注(60mg/50ml),第四次灌注时因错配塞(口替)哌浓度(60mg/10Yml),于灌注后18分钟,膀胱出现剧烈烧灼样疼痛,自行排出灌注液后疼痛稍有减轻.嗣后出现尿频、尿急、尿痛,排便时下腹堕胀,持续2周转入我院.实验室检查:尿常规WBC(?)/HP,RBC(?)/HP,尿细菌培养阴性.膀胱镜检查发现膀胱三角区及后尿道粘膜充血、血管扩张和渗出明显,有散在出血点.膀胱左侧壁有—1.5cm×1.5cm粘膜坏死灶,因
Female, age 67. Partial bladder resection was performed at a local hospital for “bladder cancer”. Cyprimary cloacal perfusion (60 mg / 50 ml) was routinely performed one week after surgery, With oral gavage (60mg / 10Yml), 18 minutes after perfusion, severe burning of the bladder-like pain and relieving pain caused by spontaneous discharge of the perfusion fluid was slightly relieved. Subsequently, frequent urination, urgency, dysuria, and lower abdominal distention Abdominal distension, continued for 2 weeks transferred to our hospital laboratory tests: urine routine WBC (?) / HP, RBC (?) / HP, urine bacterial culture negative. Cystoscopy revealed bladder trigone and posterior urethral mucosal congestion, Expansion and exudation obvious, there are scattered bleeding point. Left side wall of the bladder -1.5cm × 1.5cm mucosal necrosis, due to